Strabismus, sometimes called “squint”, “cross-eyes” and “wall-eyes”, refers to misalignment of the eyes, with one eye pointing in one direction and the fellow eye in a different direction. Strabismus is often but not always associated with amblyopia. Risk factors for strabismus include ocular abnormalities such as anisometropia (difference in refractive error between the eyes), corneal scar, congenital cataract and ocular tumour; at times, strabismus occurs without any obvious underlying cause. (In adults, strabismus can also be associated with thyroid eye disease and oculomotor cranial nerve palsies, both of which are less common in children.) Depending upon the specific indication, strabismus management includes spectacle, occlusion (if amblyopia is present) and surgical intervention. As with amblyopia, prompt and appropriate management of strabismus is essential for optimal visual development, particularly regarding stereopsis that underlie depth perception.